Renal Recovery at Different Ages
نویسنده
چکیده
While the field of acute kidney injury (AKI) research has undergone exponential growth over the past 15 years, the topic of renal recovery has only recently garnered much attention. Both lack of standardized renal recovery definitions and lack of systematic assessment of AKI survivors for chronic kidney disease development pose barriers to the complete understanding of the renal recovery epidemiology. In addition, evaluation of pediatric AKI renal recovery is further complicated by the potential AKI effects on renal development as well as a relatively greater renal reserve for younger children. The aims of this review are to review the current state of knowledge in pediatric AKI renal recovery. © 2014 S. Karger AG, Basel Published online: September 24, 2014 Stuart L. Goldstein, MD Cincinnati Children’s Hospital Medical Center 3333 Burnet Avenue, MLC 7022 Cincinnati, OH 45229 (USA) E-Mail stuart.goldstein @ cchmc.org © 2014 S. Karger AG, Basel 1660–2110/14/1274–0021$39.50/0 www.karger.com/nec All the world’s a stage, And all the men and women merely players; They have their exits and their entrances, And one man in his time plays many parts, His acts being seven ages. (As You Like It, Act II, Scene VII) William Shakespeare Targeting Recovery from Acute Kidney Injury: Round Table Conference at the 19th International Conference on Continuous Renal Replacement Therapies (Manchester Grand Hyatt, San Diego, Calif., USA, March 2–3, 2014). D ow nl oa de d by : 54 .1 91 .4 0. 80 4 /2 7/ 20 17 5 :5 9: 13 A M
منابع مشابه
Evaluating the Recovery Process of Renal Ischemia/Reperfusion Injury in Rats Using Small-Animal SPECT
Background: Renal injuries associated with ischemia/reperfusion are a prevalent clinical phenomenon that can cause the emergence of progressive kidney diseases, eventually leading to chronic kidney injuries. The present study was conducted to evaluate the results obtained from non-invasive imaging using small-animal SPECT and investigate the recovery process in an animal model of renal ischemia...
متن کاملبیحسی نخاعی در پیوند کلیه
Background: Renal transplantation is the preferred therapeutic method for patients with end-stage renal disease. Patients with renal failure have significant associated medical conditions, such as cardiovascular disease. The suitable anesthesia for renal transplantation requires minimal toxicity for the transplanted organ, as well as sufficient pain relief and maintenance of optimal blood press...
متن کاملاثر آنژیوتانسین II در هسته پاراونتریکولار در تشدیدآسیب ایسکمی- پرفیوژن مجدد کلیه
Background: The renal sympathetic nerve activity (RSNA) is enhanced in renal failure. Paraventricular nucleus in hypothalamus is an important central site to regulate sympathetic activity. There are angiotensin II (Ang) II receptors in this nucleus. The aim of this study was to evaluate the effects of angiotensin II in hypothalamic paraventricular nucleus (PVN) on renal ischemia-reperfusion inj...
متن کاملAge-related decline in label-retaining tubular cells: implication for reduced regenerative capacity after injury in the aging kidney.
Recovery after acute kidney injury is impaired in the elderly, but the precise mechanism for such age-related incompetence remains unclear. By in vivo bromodeoxyuridine (BrdU) labeling, renal progenitor cells (label-retaining cells; LRCs) were identified in tubules of normal rat kidney and were shown to be the origin of proliferating cells after injury. In the present study, the involvement of ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2014